Fig. 2. Histological observation of hair follicles and dermal thickness in the back skin of C57BL/6 mice to which test compounds were applied topically for 4 weeks. N: saline, VC: jojoba oil, PC: 3% minoxidil, E1: 3% lavender oil, E2: 5% lavender oil. (A) Hair follicles. Hematoxylin and eosin staining, × 100. (B) Hair follicle number. (C) Hair follicle depth. (D) Dermal thickness. As the experiment progressed, the hair follicle number and depth in the PC, E1, and E2 groups increased markedly as compared to the N and VC groups. The dermal layer was also observed to be thicker in the PC, E1, and E2 groups. a,b,c,d,eValues with different superscripts indicate significant differences (p < 0.05) for each given week, by ANOVA and Duncan’s multiple range tests.
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