Toxicological Research : eISSN 2234-2753 / pISSN 1976-8257

Fig. 1.

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Fig. 1. Models for dose-response curves of non-genotoxic and genotoxic carcinogens. Non-genotoxic carcinogens like as other toxic chemicals have threshold while genotoxic carcinogens have no threshold. Non-genotoxic carcinogens can be used in the society if the intake level is below the threshold. Genotoxic carcinogens are supposed to have carcinogenic risk even at very low doses. Therefore, genotoxic carcinogens are generally not be considered acceptable for use as food additives, pesticides or veterinary drugs.
Toxicological Research 2018;34:281~290
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