Fig. 3. 1,2-DCP enhanced angiogenic signaling. (A) In 1,2-DCP-treated mice, the challenged dorsal skin remained vascularized. (B) Immunofluorescence of vascular endothelial growth factor (VEGF) following 1,2-DCP treatment in mice. (C) Quantification of IHC-positive areas in the skin is shown on the right. The data were analyzed by Image-Pro Plus software. Mice treated with 1,2-DCP at each indicated concentration (0, 2.73, 5.75, and 8.75 mL/kg) for 7 days (400×, scale bar = 10 μm). The results are means ± SD of two independent experiments. **p < 0.01.
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