Fig. 2. Effect of microneedles (MNs) on the shape and weight of subcutaneous adipose tissue (SAT) in rats with high-fat diet (HD)-induced obesity. Images of SAT post MN patch application to the inguinal skin (A). The arrow indicates the SAT treated with thegelatin MN patch. SAT weight was normalized to the weight of the epididymal AT (B). Data are expressed as mean ± SEMs of five rats/group. *p < 0.05 compared with the control group.
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